First Dose to Man : general principles (Estimating Safe Dose)
Phase I trials of antitumour agents: fundamental concepts - ecancer
On Biostatistics and Clinical Trials: Phase I Dose Escalation Study Design: "3 + 3 Design"
Guidance for Industry Acute Myeloid Leukemia: Developing Drugs and Biological Products for Treatment
Designing Dose-Finding Phase I Clinical Trials: Top 10 Questions That Should Be Discussed With Your Statistician | JCO Precision Oncology
Determinants of the Recommended Phase 2 Dose of Molecular Targeted Agents
Clinical Trials and Developmental Therapeutics | Veterian Key
Towards new methods for the determination of dose limiting toxicities and the assessment of the recommended dose for further studies of molecularly targeted agents – Dose-Limiting Toxicity and Toxicity Assessment Recommendation Group
On Biostatistics and Clinical Trials: Dose Limiting Toxicity (DLT) and Common Toxicity Criteria (CTC) / Common Terminology Criteria for Adverse Events (CTCAE)
Design and Conduct Considerations for First‐in‐Human Trials - Shen - 2019 - Clinical and Translational Science - Wiley Online Library
Guidance for Industry
Illustration of the chronic dose-limiting toxicity (DLT) concept. (*)... | Download Scientific Diagram
Predefined dose-limiting toxic effects | Download Table
Predictive Toxicology Approaches for Small Molecule Oncology Drugs
Moving Beyond 3+3: The Future of Clinical Trial Design | American Society of Clinical Oncology Educational Book
Phase I trials - memoinOncology
Definitions of dose limiting toxicity. | Download Table
Prediction of Drug Approval After Phase I Clinical Trials in Oncology: RESOLVED2 | JCO Clinical Cancer Informatics
Designs of drug-combination phase I trials in oncology: a systematic review of the literature - Annals of Oncology
Predictive Toxicology Approaches for Small Molecule Oncology Drugs
On Biostatistics and Clinical Trials: July 2021
213591Orig1s000
definition of dose-limiting toxicity. | Download Table
ELIZABETH GARRETT-MAYER (SOME SLIDES BY PAT LORUSSO OF KARMANOS CANCER INSTITUTE WAYNE STATE UNIVERSITY) Phase I Trials of Chemotherapy and Targeted Agents. - ppt download
