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Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5  vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised,  first-in-human trial - The Lancet
Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial - The Lancet

JCI - Results of the CAPSID randomized trial for high-dose convalescent  plasma in patients with severe COVID-19
JCI - Results of the CAPSID randomized trial for high-dose convalescent plasma in patients with severe COVID-19

UK launches booster dose trial of seven Covid-19 vaccines
UK launches booster dose trial of seven Covid-19 vaccines

The phases of preclinical and clinical trials
The phases of preclinical and clinical trials

Dose-Levels and First Signs of Efficacy in Contemporary Oncology Phase 1  Clinical Trials | PLOS ONE
Dose-Levels and First Signs of Efficacy in Contemporary Oncology Phase 1 Clinical Trials | PLOS ONE

Ponatinib dose-ranging study in chronic-phase chronic myeloid leukemia: a  randomized, open-label phase 2 clinical trial - ScienceDirect
Ponatinib dose-ranging study in chronic-phase chronic myeloid leukemia: a randomized, open-label phase 2 clinical trial - ScienceDirect

Dose escalation design for the Part 1 of the trial. Single patients... |  Download Scientific Diagram
Dose escalation design for the Part 1 of the trial. Single patients... | Download Scientific Diagram

Diuretic Strategies in Patients with Acute Decompensated Heart Failure |  NEJM
Diuretic Strategies in Patients with Acute Decompensated Heart Failure | NEJM

Clinical and Pharmacological Effects of Apixaban Dose Adjustment in the  ARISTOTLE Trial | Journal of the American College of Cardiology
Clinical and Pharmacological Effects of Apixaban Dose Adjustment in the ARISTOTLE Trial | Journal of the American College of Cardiology

PureTech Presents Data for LYT-100 (Deupirfenidone) Supporting Design of  Dose-Ranging Trial in Idiopathic Pulmonary Fibrosis (IPF) at European  Respiratory Society International Congress 2022 | Business Wire
PureTech Presents Data for LYT-100 (Deupirfenidone) Supporting Design of Dose-Ranging Trial in Idiopathic Pulmonary Fibrosis (IPF) at European Respiratory Society International Congress 2022 | Business Wire

Effects of high-dose versus low-dose losartan on clinical outcomes in  patients with heart failure (HEAAL study): a randomised, double-blind trial  - The Lancet
Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial - The Lancet

Vaccines | Free Full-Text | The Correlated Beta Dose Optimisation Approach:  Optimal Vaccine Dosing Using Mathematical Modelling and Adaptive Trial  Design
Vaccines | Free Full-Text | The Correlated Beta Dose Optimisation Approach: Optimal Vaccine Dosing Using Mathematical Modelling and Adaptive Trial Design

Diuretic Strategies in Patients with Acute Decompensated Heart Failure |  NEJM
Diuretic Strategies in Patients with Acute Decompensated Heart Failure | NEJM

The future of drug development: advancing clinical trial design | Nature  Reviews Drug Discovery
The future of drug development: advancing clinical trial design | Nature Reviews Drug Discovery

Trial Design Including Dose Escalation and Treatment Schedule 2a)... |  Download Scientific Diagram
Trial Design Including Dose Escalation and Treatment Schedule 2a)... | Download Scientific Diagram

DESTINY-Lung02 Trial | ENHERTU® (fam-trastuzumab deruxtecan-nxki)
DESTINY-Lung02 Trial | ENHERTU® (fam-trastuzumab deruxtecan-nxki)

Safety and tolerability of bosutinib in patients with amyotrophic lateral  sclerosis (iDReAM study): A multicentre, open-label, dose-escalation phase  1 trial - eClinicalMedicine
Safety and tolerability of bosutinib in patients with amyotrophic lateral sclerosis (iDReAM study): A multicentre, open-label, dose-escalation phase 1 trial - eClinicalMedicine

فدوى الخريصي on Twitter: "The Dose Trial 💉 https://t.co/jnw6hmKvqr" /  Twitter
فدوى الخريصي on Twitter: "The Dose Trial 💉 https://t.co/jnw6hmKvqr" / Twitter

Phase 1A/1B dose-escalation and -expansion study to evaluate the safety,  pharmacokinetics, food effects and antitumor activity of pamiparib in  advanced solid tumours | British Journal of Cancer
Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours | British Journal of Cancer

A phase I, randomized, observer-blinded, single and multiple ascending-dose  study to investigate the safety, pharmacokinetics, and immunogenicity of  BITS7201A, a bispecific antibody targeting IL-13 and IL-17, in healthy  volunteers | BMC Pulmonary
A phase I, randomized, observer-blinded, single and multiple ascending-dose study to investigate the safety, pharmacokinetics, and immunogenicity of BITS7201A, a bispecific antibody targeting IL-13 and IL-17, in healthy volunteers | BMC Pulmonary

Diuretic Strategies in Patients with Acute Decompensated Heart Failure -  ppt download
Diuretic Strategies in Patients with Acute Decompensated Heart Failure - ppt download

The phases of preclinical and clinical trials
The phases of preclinical and clinical trials

Randomized Trial of a Third Dose of mRNA-1273 Vaccine in Transplant  Recipients | NEJM
Randomized Trial of a Third Dose of mRNA-1273 Vaccine in Transplant Recipients | NEJM

How a COVID-19 vaccine trial error led to an unexpected discovery
How a COVID-19 vaccine trial error led to an unexpected discovery

How to design a dose-finding study using the continual reassessment method  | BMC Medical Research Methodology | Full Text
How to design a dose-finding study using the continual reassessment method | BMC Medical Research Methodology | Full Text

High-Dose Biotin Fails in MS Trial | MedPage Today
High-Dose Biotin Fails in MS Trial | MedPage Today